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Integrin α(v)β(3) acts downstream of insulin in normalization of interstitial fluid pressure in sepsis and in cell-mediated collagen gel contraction

The administration of insulin is recommended to patients with severe sepsis and hyperglycemia. Previously, we demonstrated that insulin may have direct anti-inflammatory properties and counteracted fluid losses from the circulation by normalizing the interstitial fluid pressure (P(IF)). P(IF) is one...

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Autors principals: Svendsen, Øyvind Sverre, Lidén, Åsa, Nedrebø, Torbjørn, Rubin, Kristofer, Reed, Rolf K.
Format: Artigo
Idioma:Inglês
Publicat: American Physiological Society 2008
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2519195/
https://ncbi.nlm.nih.gov/pubmed/18552165
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00161.2008
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