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Cardiac myosin binding protein-C modulates actomyosin binding and kinetics in the in vitro motility assay

The modulatory role of whole cardiac myosin binding protein-C (cMyBP-C) on myosin force and motion generation was assessed in an in vitro motility assay. The presence of cMyBP-C at an approximate molar ratio of cMyBP-C to whole myosin of 1:2, resulted in a 25% reduction in thin filament velocity (P&...

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Autors principals: Saber, Walid, Begin, Kelly J., Warshaw, David M., VanBuren, Peter
Format: Artigo
Idioma:Inglês
Publicat: 2008
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2519167/
https://ncbi.nlm.nih.gov/pubmed/18482734
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yjmcc.2008.03.012
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