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Peroxisome Proliferator-Activated Receptors in the Modulation of the Immune/Inflammatory Response in Atherosclerosis
Inflammation has been recognized as an important hallmark of atherosclerosis. The pharmacological activation of PPAR-γ by the thiazolidinediones in diabetes, and of PPAR-α by the fibrates in hyperlipidemia has been shown to help to reduce inflammatory markers in preclinical and clinical studies. PPA...
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Hindawi Publishing Corporation
2008
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| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2519138/ https://ncbi.nlm.nih.gov/pubmed/18769491 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2008/285842 |
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