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CHARACTERIZATION OF VIRULENCE OF Leptospira ISOLATES IN A HAMSTER MODEL

Effort has been made to identify protective antigens in order to develop a recombinant vaccine against leptospirosis. Several attempts failed to conclusively demonstrate efficacy of vaccine candidates due to the lack of an appropriate model of lethal leptospirosis. The purposes of our study were: (i...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Silva, Éverton F., Santos, Cleiton S., Athanazio, Daniel A., Seyffert, Núbia, Seixas, Fabiana K., Cerqueira, Gustavo M., Fagundes, Michel Q., Brod, Claudiomar S., Reis, Mitermayer G., Dellagostin, Odir A., Ko, Albert I.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2008
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2519131/
https://ncbi.nlm.nih.gov/pubmed/18547690
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.vaccine.2008.04.085
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