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DNA binding to RecD: role of the 1B domain in SF1B helicase activity

The molecular mechanism of superfamily 1Bα helicases remains unclear. We present here the crystal structure of the RecD2 helicase from Deinococcus radiodurans at 2.2-Å resolution. The structure reveals the folds of the 1B and 2B domains of RecD that were poorly ordered in the structure of the Escher...

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Bibliografiske detaljer
Main Authors: Saikrishnan, Kayarat, Griffiths, Stuart P, Cook, Nicola, Court, Robert, Wigley, Dale B
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2008
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2519098/
https://ncbi.nlm.nih.gov/pubmed/18668125
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2008.144
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