Charting calcium-regulated apoptosis pathways using chemical biology: role of calmodulin kinase II

BACKGROUND: Intracellular free calcium ([Ca(2+)](i)) is a key element in apoptotic signaling and a number of calcium-dependent apoptosis pathways have been described. We here used a chemical biology strategy to elucidate the relative importance of such different pathways. RESULTS: A set of 40 agents...

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Bibliographic Details
Main Authors: Olofsson, Maria Hägg, Havelka, Aleksandra Mandic, Brnjic, Slavica, Shoshan, Maria C, Linder, Stig
Format: Artigo
Language:Inglês
Published: BioMed Central 2008
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2518916/
https://ncbi.nlm.nih.gov/pubmed/18673549
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1472-6769-8-2
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