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Mutations of Nonconserved Residues within the Calcium Channel α(1)-interaction Domain Inhibit β-Subunit Potentiation

Voltage-dependent calcium channels consist of a pore-forming subunit (Ca(V)α(1)) that includes all the molecular determinants of a voltage-gated channel, and several accessory subunits. The ancillary β-subunit (Ca(V)β) is a potent activator of voltage-dependent calcium channels, but the mechanisms a...

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Main Authors: Gonzalez-Gutierrez, Giovanni, Miranda-Laferte, Erick, Naranjo, David, Hidalgo, Patricia, Neely, Alan
Formato: Artigo
Idioma:Inglês
Publicado: The Rockefeller University Press 2008
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2518731/
https://ncbi.nlm.nih.gov/pubmed/18725532
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1085/jgp.200709901
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