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Mechanistic And Structural Analysis of Human Spermidine/spermine N(1)-Acetyltransferase [hSSAT]

The N(1)-acetylation of spermidine and spermine by spermidine/spermine acetyltransferase (SSAT) is a crucial step in the regulation of the cellular polyamine levels in eukaryotic cells. Altered polyamine levels are associated with a variety of cancers as well as other diseases, and key enzymes in th...

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Detalhes bibliográficos
Main Authors: Hegde, Subray S., Chandler, Jonathan, Vetting, Matthew W., Yu, Michael, Blanchard, John S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2518666/
https://ncbi.nlm.nih.gov/pubmed/17516632
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi700256z
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