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Tissue-specific accelerated aging in nucleotide excision repair deficiency

Nucleotide excision repair (NER) is a multi-step DNA repair mechanism that removes helix-distorting modified nucleotides from the genome. NER is divided into two subpathways depending on the location of DNA damage in the genome and how it is first detected. Global genome NER identifies and repairs D...

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Bibliografske podrobnosti
Glavni avtor: Niedernhofer, Laura J.
Format: Artigo
Jezik:Inglês
Izdano: 2008
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2518655/
https://ncbi.nlm.nih.gov/pubmed/18538374
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mad.2008.04.010
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