Association Testing of Novel Type 2 Diabetes Risk Alleles in the JAZF1, CDC123/CAMK1D, TSPAN8, THADA, ADAMTS9, and NOTCH2 Loci With Insulin Release, Insulin Sensitivity, and Obesity in a Population-Based Sample of 4,516 Glucose-Tolerant Middle-Aged Danes

OBJECTIVE— We evaluated the impact on diabetes-related intermediary traits of common novel type 2 diabetes–associated variants in the JAZF1 (rs864745), CDC123/CAMK1D (rs12779790), TSPAN8 (rs7961581), THADA (rs7578597), ADAMTS9 (rs4607103), and NOTCH2 (rs10923931) loci, which were recently identified...

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Main Authors: Grarup, Niels, Andersen, Gitte, Krarup, Nikolaj T., Albrechtsen, Anders, Schmitz, Ole, Jørgensen, Torben, Borch-Johnsen, Knut, Hansen, Torben, Pedersen, Oluf
Format: Artigo
Jezik:Inglês
Izdano: American Diabetes Association 2008
Teme:
Genetics
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2518507/
https://ncbi.nlm.nih.gov/pubmed/18567820
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db08-0436
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