High-Density Single Nucleotide Polymorphism Genome-Wide Linkage Scan for Susceptibility Genes for Diabetic Nephropathy in Type 1 Diabetes: Discordant Sibpair Approach

OBJECTIVE— Epidemiological and family studies have demonstrated that susceptibility genes play an important role in the etiology of diabetic nephropathy, defined as persistent proteinuria or end-stage renal disease (ESRD) in type 1 diabetes. RESEARCH DESIGN AND METHODS— To efficiently search for gen...

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Bibliographic Details
Main Authors: Rogus, John J., Poznik, G. David, Pezzolesi, Marcus G., Smiles, Adam M., Dunn, Jonathon, Walker, William, Wanic, Krzysztof, Moczulski, Dariusz, Canani, Luis, Araki, Shinichi, Makita, Yuichiro, Warram, James H., Krolewski, Andrzej S.
Format: Artigo
Language:Inglês
Published: American Diabetes Association 2008
Subjects:
Genetics
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2518505/
https://ncbi.nlm.nih.gov/pubmed/18559660
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db07-1086
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