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Pharmacological targeting of the KIT growth factor receptor: a therapeutic consideration for mast cell disorders
KIT is a member of the tyrosine kinase family of growth factor receptors which is expressed on a variety of haematopoietic cells including mast cells. Stem cell factor (SCF)-dependent activation of KIT is critical for mast cell homeostasis and function. However, when KIT is inappropriately activated...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
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Nature Publishing Group
2008
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| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2518463/ https://ncbi.nlm.nih.gov/pubmed/18500355 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjp.2008.204 |
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