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Pharmacological targeting of the KIT growth factor receptor: a therapeutic consideration for mast cell disorders
KIT is a member of the tyrosine kinase family of growth factor receptors which is expressed on a variety of haematopoietic cells including mast cells. Stem cell factor (SCF)-dependent activation of KIT is critical for mast cell homeostasis and function. However, when KIT is inappropriately activated...
Αποθηκεύτηκε σε:
| Κύριοι συγγραφείς: | , , |
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| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
Nature Publishing Group
2008
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2518463/ https://ncbi.nlm.nih.gov/pubmed/18500355 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjp.2008.204 |
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