Maintenance of Tolerance by Regulation of Anti-myeloperoxidase B Cells

Anti-neutrophil cytoplasmic autoantibodies directed toward myeloperoxidase or proteinase 3 are detected in sera of patients with small vessel vasculitis and participate in the pathogenesis of this disease. Autoantibodies develop when self-reactive B cells escape the regulation that ensures self-tole...

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Autors principals: Bunch, Donna O., Silver, Jonathan S., Majure, Melanie C., Sullivan, Pamela, Alcorta, David A., Chin, Hyunsook, Hogan, Susan L., Lindstrom, Yoshi I., Clarke, Stephen H., Falk, Ronald J., Nachman, Patrick H.
Format: Artigo
Idioma:Inglês
Publicat: American Society of Nephrology 2008
Matèries:
Basic Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2518447/
https://ncbi.nlm.nih.gov/pubmed/18650487
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2007030382
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