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Heme Oxygenase-1 Deficiency Promotes Epithelial-Mesenchymal Transition and Renal Fibrosis

Induction of heme oxygenase-1 (HO-1) is associated with potential antifibrogenic effects. The effects of HO-1 expression on epithelial-mesenchymal transition (EMT), which plays a critical role in the development of renal fibrosis, are unknown. In this study, HO-1(−/−) mice demonstrated significantly...

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Detalhes bibliográficos
Main Authors: Kie, Jeong-Hae, Kapturczak, Matthias H., Traylor, Amie, Agarwal, Anupam, Hill-Kapturczak, Nathalie
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Nephrology 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2518436/
https://ncbi.nlm.nih.gov/pubmed/18495963
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2007101099
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