Cytoplasmic cAMP concentrations in intact cardiac myocytes

In cardiac myocytes there is evidence that activation of some receptors can regulate protein kinase A (PKA)-dependent responses by stimulating cAMP production that is limited to discrete intracellular domains. We previously developed a computational model of compartmentalized cAMP signaling to inves...

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Detalhes bibliográficos
Main Authors: Iancu, Radu V., Ramamurthy, Gopalakrishnan, Warrier, Sunita, Nikolaev, Viacheslav O., Lohse, Martin J., Jones, Stephen W., Harvey, Robert D.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2008
Assuntos:
Receptors and Signal Transduction
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2518413/
https://ncbi.nlm.nih.gov/pubmed/18550706
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpcell.00038.2008
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