Stress Induces a Switch of Intracellular Signaling in Sensory Neurons in a Model of Generalized Pain

Stress dramatically exacerbates pain in diseases such as fibromyalgia and rheumatoid arthritis, but the underlying mechanisms are unknown. We tested the hypothesis that stress causes generalized hyperalgesia by enhancing pronociceptive effects of immune mediators. Rats exposed to nonhabituating soun...

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Main Authors: Khasar, Sachia G., Burkham, Jennifer, Dina, Olayinka A., Brown, Adrienne S., Bogen, Oliver, Alessandri-Haber, Nicole, Green, Paul G., Reichling, David B., Levine, Jon D.
Formato: Artigo
Idioma:Inglês
Publicado: Society for Neuroscience 2008
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Articles
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2518401/
https://ncbi.nlm.nih.gov/pubmed/18509033
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.0256-08.2008
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