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Stress Induces a Switch of Intracellular Signaling in Sensory Neurons in a Model of Generalized Pain

Stress dramatically exacerbates pain in diseases such as fibromyalgia and rheumatoid arthritis, but the underlying mechanisms are unknown. We tested the hypothesis that stress causes generalized hyperalgesia by enhancing pronociceptive effects of immune mediators. Rats exposed to nonhabituating soun...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Khasar, Sachia G., Burkham, Jennifer, Dina, Olayinka A., Brown, Adrienne S., Bogen, Oliver, Alessandri-Haber, Nicole, Green, Paul G., Reichling, David B., Levine, Jon D.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Society for Neuroscience 2008
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2518401/
https://ncbi.nlm.nih.gov/pubmed/18509033
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.0256-08.2008
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