ELEVATED LIPID PEROXIDATION AND DNA OXIDATION IN NERVE FROM DIABETIC RATS: EFFECTS OF ALDOSE REDUCTASE INHIBITION, INSULIN AND NEUROTROPHIC FACTORS

We investigated the effect of treatment with an aldose reductase inhibitor, insulin or select neurotrophic factors on the generation of oxidative damage in peripheral nerve. Rats were either treated with streptozotocin (STZ) to induce insulin-deficient diabetes or fed with a diet containing 40% D-ga...

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Detalhes bibliográficos
Main Authors: Cunha, Joice M., Jolivalt, Corinne G., Ramos, Khara M., Gregory, Joshua A., Calcutt, Nigel A., Mizisin, Andrew P.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2518323/
https://ncbi.nlm.nih.gov/pubmed/18555826
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.metabol.2008.01.021
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