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Thermodynamic Characterization of the Interaction between CAR/RXR and SRC-1 Peptide by Isothermal Titration Calorimetry
The constitutive androstane receptor (CAR) enhances transcription of specific target genes that regulate several metabolic pathways. CAR functions as an obligate heterodimer with the retinoid-X-receptor (RXR). Also part of the active receptor complex is the steroid receptor coactivator-1 (SRC-1) whi...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2518310/ https://ncbi.nlm.nih.gov/pubmed/17223708 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi061627i |
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