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TRIM28 mediates primer binding site-targeted silencing of Lys1,2 tRNA-utilizing retroviruses in embryonic cells

Murine leukemia viruses (MLVs) and related retroelements are potently restricted in embryonic cells by postintegration transcriptional silencing, likely to protect the germ line from insertional mutagenesis. This silencing is in large part attributable to the presence of a nuclear repression complex...

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Bibliografiset tiedot
Päätekijät: Wolf, Daniel, Hug, Kevin, Goff, Stephen P.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: National Academy of Sciences 2008
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC2518094/
https://ncbi.nlm.nih.gov/pubmed/18713861
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0805540105
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