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Monomeric Yeast Frataxin is an Iron Binding Protein

Friedreich's ataxia, an autosomal cardio- and neurodegenerative disorder that affects 1 in 50,000 humans, is caused by decreased levels of the protein frataxin. Although nuclear encoded, frataxin is targeted to the mitochondrial matrix and necessary for proper regulation of cellular iron homeos...

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Autors principals: Cook, Jeremy D., Bencze, Krisztina Z., Jankovic, Ana D., Crater, Anna K., Busch, Courtney N., Bradley, Patrick B., Stemmler, Ann J., Spaller, Mark R., Stemmler, Timothy L.
Format: Artigo
Idioma:Inglês
Publicat: 2006
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2518068/
https://ncbi.nlm.nih.gov/pubmed/16784228
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi060424r
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