Cytokines and their receptors in cardiovascular diseases — role of gp130 signalling pathway in cardiac myocyte growth and maintenance

Interleukin (IL)-6-related cytokines share gp130 as the signal-transducing protein. Cardiac myocytes produce various kinds of cytokines including IL-6 and cardiotrophin-1. Activation of gp130 transduces hypertrophic and cytoprotective signals in cardiac myocytes via JAK/STAT, MAP kinase and PI-3 kin...

Full description

Saved in:
Bibliographic Details
Main Authors: Yamauchi-Takihara, K, Kishimoto, T
Format: Artigo
Language:Inglês
Published: Blackwell Science Inc 2000
Subjects:
Cardiovascular Pathology in the Year 2000
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2517789/
https://ncbi.nlm.nih.gov/pubmed/10718860
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2613.2000.00139.x
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items