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The effect of IFNγ on the hepatocyte: cell cycle and apoptosis
The inflammatory cytokine interferon gamma (IFNγ) can cause cell cycle arrest and apoptosis in the hepatocyte. Primarily these processes are protective but in chronic liver disease oncogenic mutations may prosper. IFNγ signalling is discussed showing how p53 is induced to cause cell cycle arrest. Wh...
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| Autori principali: | , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Blackwell Science Inc
2001
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2517788/ https://ncbi.nlm.nih.gov/pubmed/11846838 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2613.2001.00207.x |
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