Peplomycin, a bleomycin derivative, induces myofibroblasts in pulmonary fibrosis

To analyse the mechanism by which a bleomycin derivative, peplomycin (PLM) induces pulmonary fibrosis, we investigated differentiation of rat pulmonary fibroblasts to myofibroblasts (MF). In intraperitoneally PLM (5 mg/kg/day)-injected rats, the peripheries of lungs adjacent to the pleura revealed a...

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Autori principali: Osaki, Tokio, Yoneda, Kazunori, Tatemoto, Yukihiro, Yamamoto, Tetsuya, Yokoyama, Takeshi, Enzan, Hideaki
Natura: Artigo
Lingua:Inglês
Pubblicazione: Blackwell Science Inc 2001
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Original Articles
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2517715/
https://ncbi.nlm.nih.gov/pubmed/11493347
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2613.2001.iep0082-0231-x
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