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Mechanisms of 5-azacytidine (5AzC)-induced toxicity in the rat foetal brain
Mechanisms of 5-azacytidine (5AzC)-induced toxicity in the rat foetal brain were investigated. 5AzC (10 mg/kg) was injected into pregnant rats on day 13 of gestation and the protein and mRNA expressions of p53 and its transcriptional target genes, p21, bax, cyclin G1, fas, and gadd45, were examined...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Blackwell Science Inc
2002
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2517675/ https://ncbi.nlm.nih.gov/pubmed/12383193 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2613.2002.00225.x |
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