C-Kit and Its Ligand Stem Cell Factor: Potential Contribution to Prostate Cancer Bone Metastasis

The tyrosine kinase receptor c-kit and its ligand stem cell factor (SCF) have not been explored in prostate cancer (PC) bone metastasis. Herein, we found that three human PC cell lines and bone marrow stromal cells express a membrane-bound SCF isoform and release a soluble SCF. Bone marrow stromal c...

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Hauptverfasser: Wiesner, Christoph, Nabha, Sanaa M, Dos Santos, Emanuel Burck, Yamamoto, Hamilto, Meng, Hong, Melchior, Sebastian W, Bittinger, Fernando, Thüroff, Joachim W, Vessella, Robert L, Cher, Michael L, Bonfil, R Daniel
Format: Artigo
Sprache:Inglês
Veröffentlicht: Neoplasia Press Inc. 2008
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2517645/
https://ncbi.nlm.nih.gov/pubmed/18714401
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