The effect of mutated mitochondrial ribosomal proteins S16 and S22 on the assembly of the small and large ribosomal subunits in human mitochondria

Mutations in mitochondrial small subunit ribosomal proteins MRPS16 or MRPS22 cause severe, fatal respiratory chain dysfunction due to impaired translation of mitochondrial mRNAs. The loss of either MRPS16 or MRPS22 was accompanied by the loss of most of another small subunit protein MRPS11. However,...

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Bibliografiske detaljer
Main Authors: Haque, Md. Emdadul, Grasso, Domenick, Miller, Chaya, Spremulli, Linda L, Saada, Ann
Format: Artigo
Sprog:Inglês
Udgivet: 2008
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2517634/
https://ncbi.nlm.nih.gov/pubmed/18539099
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mito.2008.04.004
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