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Modeling oncogene addiction using RNA interference
The clinical efficacy of selective kinase inhibitors suggests that some cancer cells may become dependent on a single oncogene for survival. RNAi has been increasingly used to understand such “oncogene addiction” and validate new therapeutic targets. However, RNAi approaches suffer from significant...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2517605/ https://ncbi.nlm.nih.gov/pubmed/18711136 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0803217105 |
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