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The endothelin-1 receptor antagonists ameliorate histology and ultrastructural alterations in the pancreas and decrease trypsinogen activation in severe taurocholate pancreatitis in rats

The role of potent vasoconstrictor endothelin-1 (ET-1) in acute pancreatitis (AP) remains controversial. The aim was to compare the effect of nonselective ET R(A/B) (LU-302872) and selective ET R(A) (LU-302146) antagonists on pancreatic histology, ultrastructure and trypsinogen activation in severe...

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Detalhes bibliográficos
Main Authors: Andrzejewska, Anna, Dlugosz, Jan W
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2003
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2517562/
https://ncbi.nlm.nih.gov/pubmed/14690481
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2613.2003.00359.x
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