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Vascular endothelial growth factor reduces mural cell coverage of endothelial cells and induces sprouting rather than luminal division in an HT1080 tumour angiogenesis model

Vascular endothelial growth factor (VEGF) plays a central role in tumour angiogenesis. In a mouse intramuscular tumour model using VEGF-transfected HT1080 human fibrosarcoma, we investigated the morphological features and patterns of remodelling in size-matched tumours. Compared with the control tum...

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Detalhes bibliográficos
Main Authors: Fujimoto, Akihisa, Onodera, Hisashi, Mori, Akira, Isobe, Naoki, Yasuda, Seiichi, Oe, Hideaki, Yonenaga, Yoshikuni, Tachibana, Tsuyoshi, Imamura, Masayuki
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2004
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2517531/
https://ncbi.nlm.nih.gov/pubmed/15566432
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.0959-9673.2004.00404.x
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