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Clinical implications of the basic defects in Cockayne Syndrome and xeroderma pigmentosum and the DNA lesions responsible for cancer, neurodegeneration and aging
Cancer, aging, and neurodegeneration are all associated with DNA damage and repair in complex fashions. Aging appears to be a cell and tissue-wide process linked to the insulin-dependent pathway in several DNA repair deficient disorders, especially in mice. Cancer and neurodegeneration appear to hav...
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| Autores principales: | , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2008
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2517418/ https://ncbi.nlm.nih.gov/pubmed/18336867 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mad.2008.01.005 |
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