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Modulation of inflammatory response in sepsis by proteasome inhibition

The Ubiquitin-proteasome system has recently been shown to be involved in the regulation of cytokine expression. We tested the hypothesis of whether the in vivo administration of proteasome inhibitor MG-132 can modulate cytokine response and mortality in sepsis. Sepsis was induced in mice by caecal...

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Detalhes bibliográficos
Main Authors: Šafránek, Roman, Ishibashi, Nobuya, Oka, Youske, Ozasa, Hiroyuki, Shirouzu, Kazuo, Holeček, Milan
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2517382/
https://ncbi.nlm.nih.gov/pubmed/16965564
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2613.2006.00490.x
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