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Developmental abnormalities in multiple proliferative tissues of Apc(Min/+) mice
Germ-line mutation of the Apc gene has been linked to familial adenomatous polyposis (FAP) that predisposes to colon cancer. Apc(Min/+) mice, heterozygous for the Apc gene mutation, progressively develop small intestinal tumours in a manner that is analogous to that observed in the colon of patients...
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Main Authors: | , , , , , , , , , , , , , |
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Format: | Artigo |
Jezik: | Inglês |
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Blackwell Science Inc
2006
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Teme: | |
Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2517368/ https://ncbi.nlm.nih.gov/pubmed/16709231 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2613.2006.00477.x |
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