Developmental abnormalities in multiple proliferative tissues of Apc(Min/+) mice

Germ-line mutation of the Apc gene has been linked to familial adenomatous polyposis (FAP) that predisposes to colon cancer. Apc(Min/+) mice, heterozygous for the Apc gene mutation, progressively develop small intestinal tumours in a manner that is analogous to that observed in the colon of patients...

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Autores principales: You, Shaojin, Ohmori, Masami, Peña, Maria Marjorette O, Nassri, Basel, Quiton, Jovelyn, Al-Assad, Ziad A, Liu, Lucy, Wood, Patricia A, Berger, Sondra H, Liu, ZhiJian, Wyatt, Michael D, Price, Robert L, Berger, Franklin G, Hrushesky, William J M
Formato: Artigo
Lenguaje:Inglês
Publicado: Blackwell Science Inc 2006
Materias:
Original Articles
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2517368/
https://ncbi.nlm.nih.gov/pubmed/16709231
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2613.2006.00477.x
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