Polymyxin-B hemoperfusion inactivates circulating proapoptotic factors

OBJECTIVE: To test the hypothesis that extracorporeal therapy with polymyxin B (PMX-B) may prevent Gram-negative sepsis-induced acute renal failure (ARF) by reducing the activity of proapoptotic circulating factors. SETTING: Medical-Surgical Intensive Care Units. PATIENTS AND INTERVENTIONS: Sixteen...

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Hauptverfasser: Cantaluppi, Vincenzo, Assenzio, Barbara, Pasero, Daniela, Romanazzi, Giuseppe Mauriello, Pacitti, Alfonso, Lanfranco, Giacomo, Puntorieri, Valeria, Martin, Erica L., Mascia, Luciana, Monti, Gianpaola, Casella, Giampaolo, Segoloni, Giuseppe Paolo, Camussi, Giovanni, Ranieri, V. Marco
Format: Artigo
Sprache:Inglês
Veröffentlicht: Springer-Verlag 2008
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2517091/
https://ncbi.nlm.nih.gov/pubmed/18463848
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00134-008-1124-6
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