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Not Only Enthalpy: Large Entropy Contribution to Ion Permeation Barriers in Single-File Channels

The effect of channel length on the barrier for potassium ion permeation through single-file channels has been studied by means of all-atom molecular dynamics simulations. Using series of peptidic gramicidin-like and simplified ring-structured channels, both embedded in model membranes, we obtained...

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Detalhes bibliográficos
Main Authors: Portella, Guillem, Hub, Jochen S., Vesper, Martin D., de Groot, Bert L.
Formato: Artigo
Idioma:Inglês
Publicado em: The Biophysical Society 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2517043/
https://ncbi.nlm.nih.gov/pubmed/18515367
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.108.130609
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