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Intrinsic Bending and Structural Rearrangement of Tubulin Dimer: Molecular Dynamics Simulations and Coarse-Grained Analysis

Microtubules are long polymers of αβ-tubulin heterodimers. They undergo a process known as dynamic instability, in which the ends of a microtubule switch stochastically between phases of slow growth and rapid shrinkage. The molecular mechanisms inducing the depolymerization of microtubules were attr...

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Detalhes bibliográficos
Main Authors: Gebremichael, Yeshitila, Chu, Jhih-Wei, Voth, Gregory A.
Formato: Artigo
Idioma:Inglês
Publicado em: The Biophysical Society 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2517022/
https://ncbi.nlm.nih.gov/pubmed/18515385
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.108.129072
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