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Pulmonary eosinophilia requires interleukin-5, eotaxin-1, and CD4+ T cells in mice immunized with respiratory syncytial virus G glycoprotein

Severe illness, type 2 cytokine production, and pulmonary eosinophilia are adverse immune responses resulting from respiratory syncytial virus (RSV) challenge of vvGs-immunized mice. We have shown IL-4 and IL-13 activity must be simultaneously inhibited to reduce disease severity. We now address the...

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Detalles Bibliográficos
Main Authors: Johnson, Teresa R., Rothenberg, Marc E., Graham, Barney S.
Formato: Artigo
Idioma:Inglês
Publicado: The Society for Leukocyte Biology 2008
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2516895/
https://ncbi.nlm.nih.gov/pubmed/18519743
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1189/jlb.0907621
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