Relationship of HIV-1 and SIV Envelope Glycoprotein Trimer Occupation and Neutralization

Insights into the process of HIV-1 neutralization may assist in rational vaccine design. Here, we compared antibody neutralization against the JR-FL primary isolate and trimer binding affinities judged by native PAGE. Monovalent Fabtrimer binding and neutralization showed a direct quantitative relat...

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Bibliographische Detailangaben
Hauptverfasser: Crooks, Emma T., Jiang, Pengfei, Franti, Michael, Wong, Sharon, Zwick, Michael B., Hoxie, James A., Robinson, James E., Moore, Penny L., Binley, James M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2008
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2516379/
https://ncbi.nlm.nih.gov/pubmed/18539308
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2008.04.045
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