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Loss of PINK1 causes mitochondrial functional defects and increased sensitivity to oxidative stress
Parkinson's disease (PD) is a common neurodegenerative disorder thought to be associated with mitochondrial dysfunction. Loss of function mutations in the putative mitochondrial protein PINK1 (PTEN-induced kinase 1) have been linked to familial forms of PD, but the relation of PINK1 to mammalia...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2516271/ https://ncbi.nlm.nih.gov/pubmed/18687901 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0802076105 |
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