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Cut Thy Neighbor: Cyclic Birth and Death of Recombination Hotspots via Genetic Conflict

Most recombination takes place in numerous, localized regions called hotspots. However, empirical evidence indicates that nascent hotspots are susceptible to removal due to biased gene conversion, so it is paradoxical that they should be so widespread. Previous modeling work has shown that hotspots...

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Autori principali: Friberg, Urban, Rice, William R.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Genetics Society of America 2008
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2516093/
https://ncbi.nlm.nih.gov/pubmed/18689896
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.107.085563
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