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A Theory of Age-Dependent Mutation and Senescence
Laboratory experiments show us that the deleterious character of accumulated novel age-specific mutations is reduced and made less variable with increased age. While theories of aging predict that the frequency of deleterious mutations at mutation–selection equilibrium will increase with the mutatio...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Genetics Society of America
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2516080/ https://ncbi.nlm.nih.gov/pubmed/18660535 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.108.088526 |
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