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Heterogeneity in multistage carcinogenesis and mixture modeling

Carcinogenesis is commonly described as a multistage process, in which stem cells are transformed into cancer cells via a series of mutations. In this article, we consider extensions of the multistage carcinogenesis model by mixture modeling. This approach allows us to describe population heterogene...

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Detalhes bibliográficos
Main Authors: Gsteiger, Sandro, Morgenthaler, Stephan
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2515834/
https://ncbi.nlm.nih.gov/pubmed/18644142
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-4682-5-13
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