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The role of Wnt signaling in neuronal dysfunction in Alzheimer's Disease

Recent evidence supports a neuroprotective role for Wnt signaling in neurodegenerative disorders such as Alzheimer's Disease (AD). In fact, a relationship between amyloid-β-peptide (Aβ)-induced neurotoxicity and a decrease in the cytoplasmic levels of β-catenin has been observed. Apparently Aβ...

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Библиографические подробности
Главные авторы: Inestrosa, Nibaldo C, Toledo, Enrique M
Формат: Artigo
Язык:Inglês
Опубликовано: BioMed Central 2008
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2515306/
https://ncbi.nlm.nih.gov/pubmed/18652670
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1750-1326-3-9
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