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Elucidation of the Kijanimicin Gene Cluster: Insights into the Biosynthesis of Spirotetronate Antibiotics and Nitrosugars

The antibiotic kijanimicin produced by the actinomycete Actinomadura kijaniata has a broad spectrum of bioactivities as well as a number of interesting biosynthetic features. To understand the molecular basis for its formation and to develop a combinatorial biosynthetic system for this class of comp...

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Detalhes bibliográficos
Main Authors: Zhang, Hua, White-Phillip, Jess A., Melançon, Charles E., Kwon, Hyung-jin, Yu, Wei-luen, Liu, Hung-wen
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2515274/
https://ncbi.nlm.nih.gov/pubmed/17985890
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja0744854
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