Deep Sequencing Analysis of Small Noncoding RNA and mRNA Targets of the Global Post-Transcriptional Regulator, Hfq

Recent advances in high-throughput pyrosequencing (HTPS) technology now allow a thorough analysis of RNA bound to cellular proteins, and, therefore, of post-transcriptional regulons. We used HTPS to discover the Salmonella RNAs that are targeted by the common bacterial Sm-like protein, Hfq. Initial...

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Detalhes bibliográficos
Main Authors: Sittka, Alexandra, Lucchini, Sacha, Papenfort, Kai, Sharma, Cynthia M., Rolle, Katarzyna, Binnewies, Tim T., Hinton, Jay C. D., Vogel, Jörg
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2008
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2515195/
https://ncbi.nlm.nih.gov/pubmed/18725932
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1000163
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