Defective circulating CD25 regulatory T cells in patients with chronic immune thrombocytopenic purpura

Immune thrombocytopenic purpura (ITP) is characterized by the presence of antiplatelet autoantibodies as a result of loss of tolerance. CD4(+)CD25(+) regulatory T cells (Tregs) are important for maintenance of peripheral tolerance. Decreased levels of peripheral Tregs in patients with ITP have been...

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Hlavní autoři: Yu, Jin, Heck, Susanne, Patel, Vivek, Levan, Jared, Yu, Yu, Bussel, James B., Yazdanbakhsh, Karina
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society of Hematology 2008
Témata:
Immunobiology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2515134/
https://ncbi.nlm.nih.gov/pubmed/18420827
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2008-01-135335
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