Endothelial CD47 interaction with SIRPγ is required for human T-cell transendothelial migration under shear flow conditions in vitro

Leukocyte transendothelial migration (TEM) is a critical event during inflammation. CD47 has been implicated in myeloid cell migration across endothelium and epithelium. CD47 binds to signal regulatory protein (SIRP), SIRPα and SIRPγ. So far, little is known about the role of endothelial CD47 in T-c...

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Detalhes bibliográficos
Main Authors: Stefanidakis, Michael, Newton, Gail, Lee, Winston Y., Parkos, Charles A., Luscinskas, Francis W.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2008
Assuntos:
Immunobiology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2515120/
https://ncbi.nlm.nih.gov/pubmed/18524990
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2008-01-134429
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