Phenotypic Suppression of Methicillin Resistance in Staphylococcus aureus by Mutant Noninducible Penicillinase Plasmids

Methicillin (intrinsic) resistance of Staphylococcus aureus was suppressed almost completely by regulatory gene (penI(1)) mutations of penicillinase plasmids that made penicillinase production strictly noninducible. Methicillin resistance was restored by secondary regulatory gene mutations that alte...

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Bibliographic Details
Main Authors: Cohen, Sidney, Gibson, Carol J., Sweeney, H. M.
Format: Artigo
Language:Inglês
Published: 1972
Subjects:
Genetics and Molecular Biology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC251475/
https://ncbi.nlm.nih.gov/pubmed/5086657
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