Apparent mtDNA heteroplasmy in Alzheimer’s disease patients and in normals due to PCR amplification of nucleus-embedded mtDNA pseudogenes

In an unprecedented finding, Davis et al. [Davis, R. E., Miller, S., Herrnstadt, C., Ghosh, S. S., Fahy, E., Shinobu, L. A., Galasko, D., Thal, L. J., Beal, M. F., Howell, N. & Parker, W. D., Jr. (1997) Proc. Natl. Acad. Sci. USA 94, 4526–4531] used an unusual DNA isolation method to show that healt...

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Publicat a:	Proc Natl Acad Sci U S A
Autors principals:	Hirano, Michio, Shtilbans, Alexander, Mayeux, Richard, Davidson, Mercy M., DiMauro, Salvatore, Knowles, James A., Schon, Eric A.
Format:	Artigo
Idioma:	Inglês
Publicat:	National Academy of Sciences 1997
Matèries:	Biological Sciences
Accés en línia:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC25134/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9405710/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.94.26.14894
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